Wednesday, April 11, 2012

Cigarettes as radioactive as x-rays

When I was a medical doctor in the hospital system, every now and then I needed to get a chest x-ray on a patient who was also a cigarette smoker.
Quite often, they would get nervous about the potential radiation damage from a chest x-ray. But when I told them that two packets of cigarettes gave them the same radiation dose as a chest x-ray, they would not believe me.
This raises two questions. First, how did a radioactive metal get into their cigarettes? And second, why did they not believe me?
Every year, we humans smoke about six trillion cigarettes, enough to make a chain that would easily reach from the Earth to the Sun, and back, and then do the whole trip again, just for good measure.
By 2020, cigarettes will be killing about 10 million people each year. They have already knocked off 100 million people in the 20th century, and if we don't come to our senses, they could kill one billion in the 21st century.
The radioactive metal in cigarettes is polonium-210. It was discovered in 1898 by Marie and Pierre Curie. It is extremely toxic (about 250-million-times more toxic than cyanide) and is naturally present in uranium.
Developed countries use fertiliser that is manufactured from apatite rock, and this rock naturally contains uranium which then decays to radioactive polonium-210, which enters the tobacco plant through both the leaves and roots.
When the cigarette burns, it reaches temperatures of 600–800°C, hotter than the melting point of polonium.
The liquefied polonium sticks to tiny particles in the cigarette smoke, and then preferentially lands at locations in your airways and lungs, where one pipe splits into two pipes.
Polonium-210 has a very short half-life of 138 days. It is intensely radioactive, and sprays alpha particles on to the surrounding tissues.
Now, most people would be definitely worried if you suggested that they have a chest x-ray every day for the rest of their lives. But some of these people quite happily smoke, sometimes up to two packets of cigarettes every day.
Cigarette smoke is already loaded with various chemicals that are well-known to cause cancer. It's estimated that the radiation dose from the polonium-210 in cigarettes accounts for about two per cent of cigarette deaths. That is several thousand deaths each year in the USA alone.
It was first discovered that cigarettes contained radioactive polonium about half a century ago. So how come it's not general knowledge?
The answer is simple. Big Tobacco has done an excellent cover-up job for the last half century.
Once they realised that there was radioactive polonium in tobacco, they started their own internal — and very secret — research program. They even came up with ways to drastically reduce the amount of polonium in cigarette smoke.
At one giant tobacco company, RJ Reynolds, a memo was sent, and it read, referring to the radioactive polonium, "removal of these materials would have no commercial advantage".
But there was another reason why they wanted to keep their research secret. At the Phillip Morris tobacco company in 1978, a scientist, Paul Eichorn, wrote a memo to his boss, Robert Seligman, the then vice-president of research and development at Philip Morris.
Eichorn wrote, referring to research on polonium, "it has the potential of waking and sleeping giant. The subject is rumbling, and I doubt we should provide facts."
But the big tobacco companies had yet another reason for not publishing their research. They were following their infamous motto of 'doubt is our product'.
So any tiny variation in the research done by scientists outside the tobacco industry was spun into the spurious claim that even the experts don't really know what makes smoking harmful.
Big Tobacco's internal research showed that polonium was harmful, but to quote an internal Philip Morris document from 1982, so long as they kept their research quiet, any suggestion of a link between polonium-210 and lung cancers is "spurious and unsubstantiated".
Perhaps Big Tobacco should get some of their own internal research x-rayed, so they can see through their own smoke screen.

Dental x-rays linked to brain tumours

People who get regular dental x-rays are more likely to suffer a type of brain tumour, according to new research, suggesting that yearly exams may not be best for most patients.
The study in the US journal Cancer showed people diagnosed with meningioma who reported having a yearly bitewing exam were 1.4 times to 1.9 times as likely as a healthy control group to have developed such tumours.
A bitewing exam involves an x-ray film being held in place by a tab between the teeth.
Also, people who reported getting a yearly panorex exam - in which an x-ray is taken outside the mouth and shows all the teeth on one film - were 2.7 to three times more likely to develop cancer, said the study.
A meningioma is a tumour that forms in the membrane around the brain or spinal cord. Most of the time these tumours are benign and slow growing, but they can lead to disability or life-threatening conditions.
The research, led by Elizabeth Claus of the Yale University School of Medicine, was based on data from 1433 US patients who were diagnosed with the tumours between the ages of ages 20 and 79 years.
For comparison, researchers consulted data from a control group of 1350 individuals who had similar characteristics but had not been diagnosed with a meningioma.
Dental patients today are exposed to lower radiation levels than they were in the past, but the research should prompt dentists and patients to re-examine when and why dental x-rays are given, says Claus.
"The study presents an ideal opportunity in public health to increase awareness regarding the optimal use of dental x-rays, which unlike many risk factors is modifiable," she says.
Michael Schulder, vice chairman of the department of neurosurgery at Cushing Neuroscience Institute, part of the North Shore Long Island Jewish Health System in New York, says he was not shocked by the findings.
"This should come as no great surprise given the connection between radiation and meningioma development that has been established in various other contexts," says Schulder, who was not involved in the research.
"The chance of these tumours arising in patients who were x-rayed yearly still was low. Nonetheless, dentists and their patients should strongly consider obtaining x-rays less often than yearly unless symptoms suggest the need for imaging."

Weighing up the risk

The American Dental Association's guidelines call for children to get one x-ray every one to two years; teens to have one every 1.5 to three years, and adults every two to three years.
The ADA said in 2006 there was little evidence to back up the routine use of full-mouth dental x-rays in patients without any symptoms.
Associate Professor Matthew Hopcraft of the University of Melbourne Dental School says there are no strict guidelines regarding dental x-rays in Australia.
"Dentists in Australia would normally do a risk assessment for their patients ... weighing up the risk of disease versus the risk of potential harm from radiation from the x-rays," says Hopcraft.
He says most patients would undergo one x-ray every one or two years, while a patient with a high risk from tooth decay would need one every six months.
Hopcraft says improvements in radiographic equipment has seen the dosage rate received by patients undergoing an x-ray reduce over time.
"We've moved a lot in Australian practice towards digital radiography from traditional film and that's allowed the dosage of radiation to decrease significantly as a consequence."

Piranhas leave this fish alone

It’s a matchup wor­thy of a late-night ca­ble mov­ie: put a school of starv­ing pi­ra­nha and a 300-pound fish to­geth­er, and who comes out the win­ner?

The sur­pris­ing an­swer—given the pi­ra­nha’s no­to­ri­ous guil­lo­tine-like bite—is Brazil’s mas­sive Ar­a­pai­ma fish. The se­cret to its suc­cess, re­search­ers say, lies in its in­tri­cately de­signed scales, which could pro­vide in­spira­t­ion for en­gi­neers look­ing to de­vel­op flex­i­ble ce­ram­ics.

    Marc Mey­ers, an en­gi­neer the Uni­vers­ity of Cal­i­for­nia San Die­go, has been stu­dy­ing the Ar­a­pai­ma since trav­el­ing to the Am­a­zon ba­sin and find­ing that the fish could live in pi­ra­nha-infested lakes that make mince­meat of oth­er an­i­mals.

Mey­ers and col­leagues set up an ex­pe­ri­ment that pits pi­ra­nha against Ar­a­pai­ma by us­ing a ma­chine that re­sem­bles an in­dus­trial-strength hole punch. Pi­ra­nha teeth were at­tached to the top “punch,” which was pressed down in­to Ar­a­pai­ma scales on the low­er “punch.” The scales were em­bed­ded in a soft rub­ber sur­face meant to mim­ics the soft un­der­ly­ing mus­cle on the fish.

In their stu­dy, pub­lished in the jour­nal Ad­vanced Bio­ma­te­rials, the re­search­ers found that the teeth can par­tially pen­e­trate the scale, but crack be­fore they reach the mus­cle.

The Ar­a­pai­ma scale com­bines a hard, mineral-rich out­er­lay with an in­ter­nal de­sign that helps the scale re­sist the pi­ra­nha’s razor-like bite. The mix of ma­te­ri­als is like the hard enam­el of a tooth de­posited over softer den­tin, said Mey­ers. “You of­ten find this in na­ture, where you have some­thing hard on the out­side, but it rides on some­thing softer that gives it tough­ness,” he ex­plained.

It’s a com­bina­t­ion that en­gi­neers would like to re­pro­duce for ap­plica­t­ions such as sol­diers’ body ar­mor, which needs to be both tough and flex­i­ble, Mey­ers not­ed. Oth­er ap­plica­t­ions might in­clude fu­el cells, in­sula­t­ion and aer­o­space de­signs.

  Mey­ers is an ex­pert in bio­mim­et­ics, the study of nat­u­ral ma­te­ri­als from liv­ing or­gan­isms and the pro­cesses that pro­duce them. En­gi­neers are pur­su­ing bio­mim­et­ics be­cause “we are hit­ting a wall, so to speak” in de­signing con­ven­tion­al ma­te­ri­als, he said. “We have used our in­genu­ity to the max­i­mum, but one way to overcome that is to look at na­ture… the ma­te­ri­als that na­ture has at its dis­pos­al are not very strong, but na­ture com­bines them in a very in­gen­ious way to pro­duce strong com­po­nents and strong de­signs.”

In the case of Ar­a­pai­ma (sci­ent­i­fic name Ara­pai­ma gig­as), the in­gen­iously de­signed scales serve as peace through strength, let­ting the beast co­ex­ist with pi­ra­nha when the two are crowd­ed in­to shrunk­en Am­a­zon ba­sin lakes dur­ing the dry sea­son.

The com­bina­t­ion of hard and soft ma­te­ri­als, Mey­ers and col­leagues con­tend, give the scales sev­er­al ways to re­pel the bite. The scales overlap like shin­gles on the fish, and each scale has a “very hefty min­er­al­ized lay­er on top of it,” Mey­ers said. Un­derneath, each scale con­sists of much softer col­la­gen fibers stacked in al­ter­nat­ing di­rec­tions like a pile of ply­wood.

The ex­ter­nal sur­face is twice as hard as the in­ter­nal lay­er, giv­ing the fish a lay­er of dense ar­mor. At the same time, the struc­ture of the in­ter­nal lay­er lends tough­ness to the scale, Mey­ers said. “As you stack the lay­ers of fibers in this way,” he ex­plained, “they have dif­fer­ent ori­enta­t­ions, which gives strength that is the same in all di­rec­tions.”

Peo­ple of the Am­a­zon some­times use the ridged Ar­a­pai­mas scales, which can be nearly four inches (10 cm) long, as nail files. The cor­ru­gat­ed sur­face keeps the scales’ thick min­er­al­ized sur­face in­tact while the fish flexes as it swims, Mey­ers said. Ce­ram­ic sur­faces of un­chang­ing thick­ness are strained when bent, but the cor­ruga­t­ions let the scales “be bent more easily with­out crack­ing,” he ex­plained.

The cor­ruga­t­ions, the soft but tough in­ter­nal lay­er and the wa­ter in the scales all con­trib­ute to their abil­ity to flex while re­main­ing strong, he added. It’s an en­gi­neering so­lu­tion that lets the fish re­main mo­bile while heavily ar­mored, and al­so al­lows the scales to bend and de­form con­sid­erably be­fore break­ing.

From the ab­a­lo­ne shell to the tou­can’s beak, Mey­ers said, the nat­u­ral world is re­plete with in­spira­t­ion for 21st cen­tu­ry ma­te­ri­als sci­en­tists. One of his next pro­jects will in­volve the scales of the al­li­ga­tor gar, a huge fish from the Amer­i­can South whose scales were used by Na­tive Amer­i­cans as ar­row tips. He re­cently re­ceived some sam­ples from Lou­i­si­ana art­ist Di­anne Ulery, who makes jew­el­ry from the ivory-colored, ar­rowhead-shaped scales.

Stu­dents in his lab al­so are work­ing on ab­a­lo­ne shells and sam­ples of leath­er­back tur­tle skin ob­tained from the Na­t­ional His­to­ry Mu­se­um in San Die­go, among oth­er spe­cies.

In some re­spects, the field of bio­mim­et­ics is a re­turn to the roots of ma­n­u­fac­tur­ing, Mey­ers sug­gested, when early hu­mans crafted from leath­er, bone and wood. “We’ve pro­duced ma­te­ri­als with much high­er per­for­mance, but we’re reach­ing the lim­it with syn­thet­ic ma­te­ri­als,” he not­ed. “Now we are look­ing back at those nat­u­ral ma­te­ri­als and ask­ing, ‘how does na­ture put these things to­geth­er’?”

When not re­searching or teach­ing, Mey­ers al­so is a suc­cessful fic­tion au­thor. He has pub­lished two nov­els, “Mayan Mars” and “Chech­nya Ji­had.” He is cur­rently look­ing for a pub­lish­er for his third work of fic­tion, which takes place in the Am­a­zon and fea­tures, he said, pi­ra­nhas in spec­tac­u­lar fash­ion.

 

SV Vedic University Tirupati PG and Research Admissions 2012

Sri Venkateswara Vedic University, Tirupati (SVVU), also known as Sri Venkateswara Veda Viswavidyalaya has issued announced admission for the academic year 2012-13. Admission to various UG, PG, M.Phil and Ph.D programmes will be based on the entrance examinations to be conducted by Vedic University. SVVU is providing education free of cost along with free accommodation, clothing and hostel facilities. Admitted candidates will also get scholarships for all PG, M.Phil. and Ph.D. courses. The Vedic University is offering these programmes in the disciplines of Veda Adhyayana, Agamadhyana, Paurohityadhyanana and Veda Bhashyadhyayana. The University is funded by TTD. Details can also be obtained from www.svvedicuniversity.org . SV Vedic University is offering three year Sastri Course (graduation) and two year Acharya Course (post-graduation) in the following subjects:

1. Vedadhyayana: Rigveda (Sakala) / Krishna Yajurveda (Taittiriya) / Suklayajurveda (Kanva) / Samaveda (Kauthuma)
2. Agama: Vaikhanasagama / Pancharathragama / Saivagama
3. Paurohitya: Asvalayana Paurohitya / Apastambiya Paurohitya/ Vaikhanasa Paurohitya / Paraskara Paurohitya
4. Vedabhashya: Krishnayajurvedabhashya / Suklayajurvedabhashya (Kanva)

Selection of candidates for admissions will be done based on separate Entrance Test to be held by SVV University. SV Vedic University also offering UG and PG, M.Phil and Ph.D. Courses in Vedic Studies and other areas. These are 1. B.A. Vedic Studies 2. M.A. Vedic Studies 3. Certificate Course in Vedic Mathematics 4. M.Phil Courses (Visishtacharya Course): Veda / Veda Bhashya / Pourohitya / Aagama / Mimansa 5. Ph.D. (Vidya Varadhi).

Interested candidates can see the website www.svvedicuniversity.org for details of eligibility, age limits, entrance test pattern, syllabus and prospectus. Last date for receipt of filled in applications: 07/06/2012. Contact for details: 9000688969 / 0877- 2264 651. Address: Registrar, Sri Venkateswara Vedic University, Alipiri- Chandragiri Bypass Road, Tirupati, Andhra Pradesh.

NTR University PG Admissions Counseling Schedule 2012-13

Dr. NTR University of Health Sciences, Vijayawada has issued Counseling schedule notification for provisional admission into Post-Graduate Medical Courses for the academic year 2012-13 in the campus and its affiliated colleges in Andhra Pradesh. All the candidates qualified in the Post Graduate Medical Entrance Test 2012 (PGMET) held on 11-03-2012 are advised to attend the admission counseling as per the schedule given below. They should produce all original certificates and with University fee as stated in the notification at the time of counseling:

Venue for the counseling is Dr. NTR University of Health Sciences, Vijayawada. Physically handicapped candidates should report at 10 AM on 13 April 2012. They should attend before the Medical Board with all the original certificates. Following is the schedule for 85 percent of local seats to be filled through this counseling. Reporting time for all days is 8- 30 AM. Counseling will be held from 16th April 2012 to 23rd April 2012. Local area candidates of OU region should attend during 16 -18 April, AU area candidates between 19-21 and SVU area candidates between 22-23 April as the ranking order in various categories.

Counseling for 15 percent unreserved seats will be held on 25 and 26 April 2012 at 8-30 AM for all the candidates. All the selected candidates should pay Rs.10,600 and Rs.13,600 for admission into Government and Private colleges respectively on the day of counseling. This should be paid in the form of DD drawn on any nationalized Bank in favour of the Registrar, Dr. NTR University of Health Sciences, payable at Vijayawada. Tuition fee has to be paid to the college at respective colleges.
More details can be obtained from www.ntruhs.ap.nic.in

EAMCET 2012 Hall Tickets Download - Corrections to EAMCET Applications and Read more: http://www.apcollegeadmissions.com/2012/04/eamcet-2012-hall-tickets-download.html#ixzz1rlpfXAjf

Did you enter any mistakes while applying online for the EAMCET 2012? No need to worry. You can correct them through the procedure given by EAMCET 2012 authorities. You can made corrections in the EAMCET online applications forms till April 25, 2012. Candidates should follow this procedure to request any corrections. The Eamcet hall tickets will be ready by 26th April 2012 and no corrections will be allowed from that date. Candidates can download EAMCET 2012 hall tickets from www.apeamcet.org. You can use the said website for any corrections on your applications.

EAMCET 2012 Convener, Prof. N.V. Ramana Rao informed that candidates who want to make changes in online applications submitted for EAMCET 2012 can send an email to ‘convenoreamcet2012@gmail.com' . The mail should give details such as registration number of EAMCET application or Intermediate hall-ticket number along with identifying the mistakes to be rectified. Candidates can also check their applications for the mistakes on the website www.apeamcet.org and send a mail to the EAMCET office with all the relevant details. It is informed that most of mistakes are related to minority status and wrong entry of date of birth. The authorities will tally the details with the data available at the Board of Intermediate Education. Any mistakes will be automatically rectified by the online system. But candidates should check their applications for any mistakes and bring them to the notice of the authorities.

The submission of online applications for EAMCET 2012 is continuing with the provision of payment of the late fee. Candidates who have paid registration fee but not submitted their applications before the 30th March 2012 have to pay the fee again as their earlier transaction will not be valid. Interested candidates can submit application forms till April 9 midnight with a fee of Rs. 750 which also includes original fee. You can submit the same till April 19 with a late fee of Rs. 1,250 and till April 28, 2012 with a late fee of Rs. 5,250. The last chance to submit the applications is May 9, 2012 with a late fee of Rs. 10,250.